Ans: D
Let $f(x) = 3^x$. The above figure is the graph of $y=f(x)=3^x$.
$\begin{array}{rcl}
y & = & -3^{-x} \\
& = & -f(-x)
\end{array}$
That means $y=-3^{-x}$ is the image of reflecting $f(x)$ along the $x$-axis and then reflecting along the $y$-axis. Therefore, D is the answer.