Ans: D
$\begin{array}{|c|c|} \hline
\mbox{Rotation anti-clockwise} & \mbox{Coordinates} \\ \hline
0^\circ & (x,y) \\ \hline
90^\circ & (-y,x) \\ \hline
180^\circ & (-x,-y) \\ \hline
270^\circ & (y,-x) \\ \hline
360^\circ & (x,y) \\ \hline
\end{array}$
$\begin{array}{|c|c|} \hline
\mbox{Rotation anti-clockwise} & \mbox{Coordinates} \\ \hline
0^\circ & (x,y) \\ \hline
90^\circ & (-y,x) \\ \hline
180^\circ & (-x,-y) \\ \hline
270^\circ & (y,-x) \\ \hline
360^\circ & (x,y) \\ \hline
\end{array}$
According to the above table, the coordinates of its image are $(4,-3)$.